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While the evidence for this with secretagogues is much weaker than with exogenous GH, it is worth noting for individuals with a personal or family history of certain conditions
The driving force for uptake of amino acids by this group translocation type of mechanism is the destruction of the glutathione, for the Cys-Gly moiety is also degraded, by cysteinylglycine dipeptidase
In addition, GSH can also become depleted as a result of toxic exposure, certain disease processes and old age
Dagda RK, Cherra SJ 3rd, Kulich SM, Tandon A, Park D, Chu CT (2009) Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
Archived from the original on 1 February 2014
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